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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28e7387ff76d5f6e9175568d80a184920908c5a2f8d9e2077f2848e62452be40' 
  AND token = 'jIVVHi8iAmaghKtWLTUGLv4BSaUzxJ2xa9VdJTY92TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}