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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49c25fd7e1b205e2379a6518104f05a21ed4482f2a4d72da580c35a54598e40' 
  AND token = '7LnmR9U5RpwlX3ZpHc4XZ1AefEPTaJT9bVW2QJ1fDO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}