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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e46a7952d7dfe0dd016bc86b7ec87648ce39b850d7ca6be03c6275016259422' 
  AND token = 'ux1K22Kdo+HGU3ojloJA1JkaUThuyhlO5sGCx2iAFPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}