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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2641d39d565710389068f4dafb07f6120e82f84fc732b5342c5d53158a1e903d' 
  AND token = 'fIxkrO7EHTLMVDd5mWSCM/wKLSSLHKfBfQk5gzoJ6XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}