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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a4cc36a978fb8fe72c04660c914b916f24856fea3ce693610b48993782cac43' 
  AND token = 'jAMmaUm+peDe4SuxA7/3wPHLUVC7TB0HC9WbHPavXAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}