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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6fdb63bd254c9c8843044eac7fc55e59fb4e8c70e6e673fb2db826339fd88f' 
  AND token = '9hY6VIA1mb+p2VVHo5E1U1/WR2ZV08nP1fpKZZ1jNDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}