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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a53d916de5d77626e4a162070785a241dddffda88ca79b400cd2a1942b42acd' 
  AND token = 'yrC49FI0mI0jUibWv+/XFHtXT519mFQSWsfdrpLB9G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}