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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3c949b5a809dd4af4359e1ac5948207638a2d9bd498cb7894a43b102dc507d2' 
  AND token = 'gFHny8NcsTAQa6qD6rGhBq3hUmjHiGxFTUPGHZ1DkTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}