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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0458cc0a481e88968ee9c7156b8f2d67977b281e5a6d620e901be849b73475' 
  AND token = 'l0AlLusQA0XIonTRP96wKNonuPMuB/sf5vA0V16gek8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}