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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50819506ccbe7433820a6df7338c95c7f1cd05fc804c81dffd11beaae3f24688' 
  AND token = 'H5m9CsiyQ4/kTxba5ezrdH3G6dGWjjZtiyxqLiaxwDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}