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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b41d963d2f689874fe0b2f691a994706bec410174d5e763d246a6bf3803975a0' 
  AND token = 'wG9eomtUFaddx2gkficGGHey3S8oyULunLZd9XIWz90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}