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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed3e07f8091cdbf235e9a6493909801fa8b5792d5d0d1299a1c699b85eb6c68' 
  AND token = 'EnfmUQ0PXPjRamxZRvcKHWuHoSJ0HCneDe5Gx3WYQd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}