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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b4a91bcb267daf3e2bafb25845a8aceff1af69a6ad3a736824ac39f0774dd00' 
  AND token = 'wlWI10mr2BMwmCORkTXKu3B16hrQEpAe2Lrdn8Ye6IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}