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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64816de24499b7f2e6c8ca5882429bf4262be99cd00bc5d21fb31a46e0959171' 
  AND token = 'eIHsnguCbfD6NC4DWJ2iHXpDgL7EQyYMTMKm/SpYUFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}