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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc243e487b0a5ec26b9c005efeb7e293442ae7293656f50b36e1918545d7728b' 
  AND token = 'BVpuuvZJ4UUH+A1HaSw2CvpfSZm0ytH317wf02pCid0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}