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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37fbe6c771a016e3ae7c5ef68188ce73cbd4b12a494e8f9f715fe8e103171e1d' 
  AND token = 'YPAmUpmwj6Fg628Y2Lze2orHj3Qm1T9BqVD08vL1pYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}