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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a584a701558d7cc9fea4d98d4a64a0932305a89591d49d10048f64b545d155cd' 
  AND token = 'GDGfU1DcgMEscmM+rs+oORNg2QLTUV8WE3JUK08TOHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}