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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be4cbf5c0b29ab2342f0e4db88ab10e612fd9b04f70668458fc51c75a2870ca4' 
  AND token = 'B3nt+CDT0MwimsKWiLfWDwRTCOtQaSRQkbCNOIbq0Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}