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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57c1a5e961c0e5ea4033ba49ea5fa15c883e0aaad4a98da3cba92f6b7ac63b48' 
  AND token = 'GMxN3kk12ZZd8F6VZXfczfY55AM31dlDGyR8v67YIoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}