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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6a78a4c3c050ba99a05ae4ccbde9838b0e2111ee12b45f88283b24c26f425f6' 
  AND token = 'xNm5qlsz31Lu2CcIyBze2e2zb/wTffSZEfJT+YS46vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}