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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8271b274a203118369a76eaedd61db27442628da2de1b6c38dcc972fdc12558' 
  AND token = 'rTK14JnascvZ16bfZIO5RMzIZr+vGNhLudvZ/GG6XDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}