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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7868e8e69143ccaadc3a4802c5848242f3f9e51be05c1bfd4c42b023e5f7f3' 
  AND token = '4pUMlibBxKRLR1IZR2hMEZPgayW1khE5bHk4V2ydPZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}