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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ae12ee419ef2a46cbdea6b4c1772a4833d63648e3309a48b4cb5bc988d1a842' 
  AND token = '4EX89eIbweWOSC+oiR57GjUp3k1ahN2XjvlvzqO4wDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}