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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee28375a69c7eef8d2a510c6b1cbe3af7725cb1a6545b37dbef874f6841f83f8' 
  AND token = 'bAXBV5oTAVD0p+/g73z/RFMdAgQ6bCZoQO0Uf/LfH/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}