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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd327b06ec62b6ebc44c0c808a1942a5812173bf6d65886d3ca5bb4f1901b475' 
  AND token = 'VrpJbvt6RJ60l1D/nVmuY4nrc0gVnp7n+pQLP4yAvPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}