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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '154482e333d4cd3dd3aa9a785a441453c45bb610be396e353a12eeafe9a0583f' 
  AND token = '5w1IweEkD8NLQv3uWjfCXZMCnXVus1P+kZHWlZ6YESk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}