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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a29a2a07bb888d7affb9fff07214ce0c235672af5a1f93131901fc2d868b6f6' 
  AND token = 'BtO2gJW+rZrbKvySiCFyE7tgTq+qRyVbWKOjMwA290k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}