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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94506d8a4a6bce9e8ed4164b3f2ce4b6924f171e5d579d7a60072b1f3f190781' 
  AND token = 'Eggx6O1DUAxBJWbRrkqHrh0AbEW0ImfPLPQ/9X0E8KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}