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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a00d098bceba09c39279465aac12b607cc3dd55dd6a377c765feadcda22b5896' 
  AND token = 'xZfLQLInz1ZCOq8fHINHGYmUj5D9CrXOlH5Y1gs8JhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}