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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df8b8ff432197e918913746f165379f3e116b7e9ba1afa34c1c557b90b27fd50' 
  AND token = 'Ixp7TC6CLPT1CQS5lT2WWe9pu37MjuMqBrVx79AOIL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}