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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3a29e0683b0d48d3bfb1cfa10f82c45c7db530caaa71fe01e7b839df62a9442' 
  AND token = 'soH5zGI4HCyoLLAJAEtv6nYrYkcsgRf1IpQGi2L3lDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}