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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6648c1ef6cceae558ee64d116afd0864986524f3d6d177920905a1d26a42c83e' 
  AND token = 'mYOKmWMTqf43uSk7x/IPLHyjJPcqoBiKMFcRAuGCRqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}