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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449432e9b5255d75c03fdbdddfb9bd76af0b9be136a87eb0e9bc79a9550214d5' 
  AND token = 'z0+c3EZYo48VOAzUTBoKcoEjwgFw16yOOvdQaEcNP+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}