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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a221cb5929b5300d4a5fb25ae7e55cb5dd77d91c9ef36185620335de55519f' 
  AND token = 'Mr0Kw5fYZALYrScIs7Ws44A9sM0Pf/1SMMXS6iVRtXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}