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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7473ae99f1e466b3e77e29813d5d09f8012aad40d8ac0698309f5f9af7358ec2' 
  AND token = 'yi5RiMFLx4XiPPMEPGET9jyopWsyu7MvnOPkOL9DJVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}