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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3789ddd07f75b93a16758bb569ecfef1c917b68d042d22be70d2d6fcd20b521e' 
  AND token = 'DTKM0heg+xJxDmsruewmUmvJo+tQ0fKY3WXbb+vytdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}