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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea62736477edb81e10d9c56a5eb66c1fc652c7538a65ae2241b449026d5df56' 
  AND token = 't100M4s8Zo52rrYqHVmMssnl4oKrxmah0763r51DsrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}