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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e7d39d74f9568b10a526eb113520aee86edea6a15ecbc800a22852d7297a64' 
  AND token = 'phW7n9jhAzsTsfTnhAw0MSIIt9f5s/UZd9fetuF1Hbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}