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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4845a21a228789d6eb9ecea9471c5418774849c466e2456e5868869a14abdb4' 
  AND token = '8F9IhyEwsUMJ/OlOzi9opMLro+M+E/lKcvia0+7X39w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}