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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1575b02ae1e8a6a4e638b2b60a886be0c16c984a9769d47f781c24c510137d1' 
  AND token = '29NXw3bfqjFp9tbb0CInPONaWedpHQucRkeB5ShejOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}