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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef82fcf04676552d815a2e1f1498becd890990408f02e9cb0002f3158f1128cf' 
  AND token = 'P2OcrTE6/naVCsXeEEUAsN9OI4UhQ1XqtCpj9MPjM7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}