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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f09cb75f08bbb82c1101cd2a7254712bc13614f0ddec6a43cea9cd8dab28f2f' 
  AND token = 'B48zVZDWQmSI7KEp7kz+FYMnmrmz2fyFGgIpgpx94R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}