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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17281aef0cb8dc3f889a842a9f9c85aecc779e6261bc2a0509bc3aaee111f259' 
  AND token = '/WfHJGTIMMSOvabLw7ZbCKRXJMKlKG97IyX1dG3IeX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}