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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1722747c2b50a6a0ee96a1801eca5f3c7b518e3bf8480a4568c35ce3b4171f1f' 
  AND token = 'wv/s4rbeoQ/rRp/U2OttkmpmN4VIEYvmrhxrl28VLKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}