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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b36321f1a2fa9bad489c67a943bada6d51fcfeaabe22067c27fa9d208d68a5e8' 
  AND token = 'w+BjRHhGTc52rs65nTuvkmrVN0750zO0FlIJzXbNAaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}