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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd72d49386e805548dbfbc0fa4fb736a1a86a7b2eb494239d04dfdb7282542d6' 
  AND token = 'D1/sbJOxXPYJ3VnTo/B02vIfC/bij+fdt7g5uSTQcLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}