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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c53ab509c3d55e43278f68b5321f7ca587f1619c72e8c60347feb914c0e443' 
  AND token = 'fjS3lXfPsYL2kUmB8VJtVXCLhbOxNmYkbanSeKyVg4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}