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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b60cd8fef09dcc49614ca8752f35f431d0c6bcfe8274c2f2651f2cb2d46120' 
  AND token = 'R+YbUsUTWSgmmVTWH9hH+ZglcKxwgG0d9T3WBs0v7K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}