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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aec2aa4f363e8daab17c9d3c7b7bba5afc2c561df0563aca0240ba17f2d4e0ee' 
  AND token = '/G6QIdQYBgrVxz3Mscmjq2en4d5ZhNgbGZXYyNppV/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}