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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f06a1320c5d34e0f9de2439d33665ca9f40298b5024ff8f49093cb599a6e15d8' 
  AND token = 'mkUehsiBW2VRWTALXtc0VQoCXL1s7MThPRByAQRhsTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}